I just spent the day at my local performance shop and a guy with a sweet bio system pulled in with problems.
First off the truck is a D-max '03ish so I don't know if this helps.
His problem was driveing on bio his truck would ''shutter'' a little until he would switch back to #2.
He has a nice set-up with a fuel heater and a Fass.
But his fuel preasure was to high. Something about D-max's not likeing alot of preasure to the pump even though its the same CP3 as the Cummins.
Anyway today we tinkered with the Fass to lower the preasure, but couldn't get it low enough, I think 13psi is were we finally called it good enough.
When the guy pulled in the truck was smoken white out the pipe bad.
We removed the fuel filter on the truck (WIX) and low and behold the damn thing had calapsed inside.
Never seen anything like that.
There was alot of talk about the bio being a different viscosity and such, but after the filter was changed the thing stopped smoken and ran smooth.
Don't really know what any of this means, but the bio does something different with the lift pumps preasure wise and may have had something to do with the calapsed filter...Don't know.