To me? No, I have been seeing to many folks having surge and other issues with the Quad box, enough so that I would not feel comfortable recommending it right now. They (Quad) are working away like crazy on it though so that will likely change. My favorite box for these trucks right now is an Edge/Juice since you get gauges and performance all in one, and a fuel pressure gauge is a MUST! on these trucks.
The stock clutch on a 5spd will hold up to a surprising amount of HP if driven correctly, but do not expect it to last if there are already some serious miles on it, just plan to upgrade to a Southbend CON O down the road ad be done with it.
Get the box in first, THEN start looking at sticks, for the $$ spent a set of RV275's and a good box are hard to beat for a fun to drive rig. Start getting much bigger than that and aftermarket air will be called for, start small, then step up.
Fuel system, absolute gotta have, relocate the stock pump to the frame by the tank or go with an Airdog or FASS, stay away from the Holleys, my luck as not been that good with them.