I have measured everything up for a swap like this and it comes up short. The F150 just does not have the room under the hood for everything needed. Maybe if it had a suspension lift AND a body lift it could be done. But then the radiator would have to be put somewhere else or not run the manual fan and build your own front clip to support the grill and all. The height, width, and length of the 6.0 is just too much for the F150. I couuld keep going with what is all in the way...but just go measure it for yourself and you will see what I am talking about. The mounts would be the easy part. Just my opinions.