On the bigger tunes these trucks clean up good when turbos light. Point being I think you could just push more fuel instead of adding more air. Add the 310 tune and a wastegate for the back pressure issues these have. As long as you dont beat on it too much it should be okay. I am gonna go with the 250 and that is it until the majority of people with big tunes prove how to solve the back pressure issues that blow head gaskets and cause puking.
Knock on wood running 275 (have 310) with zex kit and have not had any problems yet. Installing studs in the spring ,winter not alowing us to play much. Not sure which tip we used just grabbed the biggest and let her rip. And yes it does wake it up, running 22.5 daully and it breaks loose and then the fun begins:woohoo:
Just be careful with the N2O. It does increase the drive pressure and can stretch the headbolts. I would wait for headstuds then spray the hell out of it.