They work fine on the street if you have the proper heat exchanger and fan setup. Only reasons to go this route on our trucks IMO are;
1. Setup with reservoir that can have ice added at the track. Hence giving additional benefit.
2. If packaging limitations underhood do not allow a sizeable A2A intercooler.
We use W2A with a small radiator as the heat exchanger on our turbo hayabusa setups and they work great. In fact they work better than our A2A setups while taking up less space.
It all comes down to the cores and heat exchanger you use.