I daily drive and tow with my p-pump 24v. 15 months and 25,000 miles so far. 15-17 broken injection lines so far too. I cheaped out when I set it up and went with used lines that were hand bent, straightened, and rebent. I replaced those piecemeal with Cummins stock VP lines that I rebent. Some of those broke too, so I ponied up for a prebent set. After 6 of those failed in an 8 month span I put on a full new set of 6 in October. 9500 miles later, tonight, #2 cracked right under a clamp.
I'm ready to put a 12v head on this damn thing. I'm kicking myself for not doing that when I put this engine in. Probably going to flush another $80 down the toilet tomorrow if my local Cummins shop has any VP lines in stock so I can make my 1200 mile weekend trip as planned with all 6 firing and without soaking my trailer and load in $4.40/gal fuel.
Other than that, it's been great. The 24v donor was an ISB205 from a bus application. I ran the stock 12v 215hp cam pump with stock ISB205 injectors timed to 20* and HX35 with no gate (failed actuator that I've never fixed...). Kept the mechanical 12v lift pump, hence the 12v cam. Hard start when cold, high egts, great power. Swapped in a Big Stick cam and set timing around 17. Starts well now but the lost timing and cam gains pretty much cancelled each other out. And I definitely lost some low end. Took too much timing out... I'd like to get some RV275s popped closer to P-pump pressure next to get timing back more aggressive, and get a WG back on the HX35 and limit boost around 31-33 where it used to be to keep it from blowing such hot air on the top end and get my EGTs fully fixed.
Not pushing my stuff as hard as most of you do, but that's my experience so far. I'd love to know what the rest of you are doing to make your lines last. I have line-to-line clamps pretty much everywhere one will fit. when I swapped the set in October I tried to get at least one of the line-to-intake cover clamps from my 12v to fit but couldn't. The ones from the 24v weren't serviceable after tear down so I couldn't try those....