I don't know that I would go with that assumption. I know several people who have ran the GTX4508R as a single on Duramax's and they blew up quite quickly. The journal bearings are cheap and easy to rebuild.
I went back and forth on this for a long time between the GTX4508R and a S480. I ended up with FI's Billet S480 with a race cover. THe compressor wheel isn't just a billet copy of BW's, it's got a freaking 120mm exducer on it. So far I couldn't be happier, it spools a lot faster then I had thought it would.