My last couple setups on my truck I have been running no intercooler. My thoughts were that I was going to be spraying one small stage of nitrous most of the time and that would be my cooling factor. I was going to add stages on top of it for power.
I found with my setup it was just making so much power I never even ran nitrous (because I am a b!tch). The problems I ran into is although the setup made power, it just ran too damn hot. Because it ran hot I had to run looser piston to wall clearance to keep pistons/cylinders from scuffing up. This caused a lot of blowby issues with 130+ psi of boost. It would leak or spray oil all over so I was pretty much limited to dirt drags. Maybe a different ring/hone combo could of helped me some, but I tried a number of different things and always had the same blowby issues.
I have gone through a number of turbos with the last couple setups and shrapnel was never an issue. Put probably a quarter of my compressor wheel through the motor and couldn't even tell. Maybe the pieces where so small it didn't make a difference, idk.
Next year plan on running a smaller a2w, tightening up my piston to wall clearance, and running a forged piston with more ring options to try and resolve my blowby issues. I am pondering water injection as an alternative to the a2w but I have no experience with it so Im not sure if I will go that route.
Before anyone asks how hot my setup got, I melted my egt prob off and could never get it working again after that.
So I would not suggest running no cooler/injectable of any kind unless you know your setup runs cool enough to not fuk chit up.